1986•Antimicrobial Agents and ChemotherapyOpen access
Influence of subinhibitory concentrations of clindamycin on opsonophagocytosis of Staphylococcus aureus, a protein-A-dependent process
E. M. Veringa, J. Verhoef
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Abstract
Incubation in subinhibitory concentrations of clindamycin enhanced the uptake of protein A-rich Staphylococcus aureus strains by polymorphonuclear leukocytes. This enhancement of uptake appeared to be due, in part, to a reduction in the amount of protein A at the bacterial cell surface by clindamycin.