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2004•Archives of Disease in ChildhoodOpen access

Response to salbutamol by wheezy infants

Richard J P G Chavasse

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Abstract

We previously reported a randomised controlled trial of β2 agonist in wheezing infants.1 Within this paper we reported no measurable physiological response to 400 μg salbutamol. Pulmonary function tests were performed after the completion of a symptom diary study and prior to enrolment in a study of inhaled corticosteroid.2 Raw values of maximum flow at functional residual capacity (V′maxFRC) and bronchodilator response were reported as there were no suitable standard values for V′maxFRC available, either from our laboratory or internationally. Subsequently, collaboration between centres in …

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We previously reported a randomised controlled trial of β2 agonist in wheezing infants.1 Within this paper we reported no measurable physiological response to 400 μg salbutamol. Pulmonary function tests were performed after the completion of a symptom diary study and prior to enrolment in a study of inhaled corticosteroid.2 Raw values of maximum flow at functional residual capacity (V′maxFRC) and bronchodilator response were reported as there were no suitable standard values for V′maxFRC available, either from our laboratory or internationally. Subsequently, collaboration between centres in …

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Available abstract

We previously reported a randomised controlled trial of β2 agonist in wheezing infants.1 Within this paper we reported no measurable physiological response to 400 μg salbutamol. Pulmonary function tests were performed after the completion of a symptom diary study and prior to enrolment in a study of inhaled corticosteroid.2 Raw values of maximum flow at functional residual capacity (V′maxFRC) and bronchodilator response were reported as there were no suitable standard values for V′maxFRC available, either from our laboratory or internationally. Subsequently, collaboration between centres in …

Key concepts: Salbutamol, Medicine, Bronchodilator, Bronchodilator Agents, Functional residual capacity, Asthma, Corticosteroid, Agonist

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