[Comparative therapeutic effect of bronchodilator aerosols and salbutamol cyclocaps].
Milica Ninković, D Bjelajac, B Ranković, V Dangubić, Goran I. Plavec
Abstract
Milica Ninković, D Bjelajac, B Ranković, V Dangubić, Goran I. Plavec
Abstract
In 12 men, atopic asthmatics, the bronchodilator effects have been studied after inhalation of 400 micrograms of salbutamol cyclocaps and bronchodilators in aerosol (40 micrograms of ipratropium bromide, 400 micrograms of fenoterol, 100 micrograms of fenoterol + 40 micrograms of ipratropium bromide and 200 micrograms of salbutamol). Bronchodilators were inhaled in different days at the same time. FEV1 measurements were repeated after 30, 60, 120 and 360 minutes and the values were compared with those obtained prior to inhalation of the drug. Although a better bronchodilator response to salbutamol cyclocaps is statistically insignificant, its longest maintenance make it suitable for the long-term therapy.
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In 12 men, atopic asthmatics, the bronchodilator effects have been studied after inhalation of 400 micrograms of salbutamol cyclocaps and bronchodilators in aerosol (40 micrograms of ipratropium bromide, 400 micrograms of fenoterol, 100 micrograms of fenoterol + 40 micrograms of ipratropium bromide and 200 micrograms of salbutamol). Bronchodilators were inhaled in different days at the same time. FEV1 measurements were repeated after 30, 60, 120 and 360 minutes and the values were compared with those obtained prior to inhalation of the drug. Although a better bronchodilator response to salbutamol cyclocaps is statistically insignificant, its longest maintenance make it suitable for the long-term therapy.
Key concepts: Ipratropium bromide, Salbutamol, Bronchodilator, Fenoterol, Inhalation, Medicine, Anesthesia, Asthma