2009•CellOpen access

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

Timothy R. Peterson, Mathieu Laplante, Carson C. Thoreen, Yasemin Sancak, Seong Anthony Woo Kang, Walter Michael Kuehl, Nathanael S. Gray, David M. Sabatini

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Key concepts: mTORC2, mTORC1, PI3K/AKT/mTOR pathway, Cancer research, Protein kinase B, Biology, P70-S6 Kinase 1, Cell biology

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DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival — Research Paper | ScholarLens