Celecoxib-induced cholestatic liver injury
Timothy J. Judson, Rachel Feldman, Kevin A. Wood, Carlos Pagan, David Wan, Todd Cutler
Abstract
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Timothy J. Judson, Rachel Feldman, Kevin A. Wood, Carlos Pagan, David Wan, Todd Cutler
Abstract
Open-access reader
Although drug-induced liver injury is common, physician awareness of specific drug reactions is often limited. Celecoxib-induced drug injury has not been widely reported. We describe the case of a 28 year-old woman who presented to the emergency department with cholestatic liver injury following 13 days of celecoxib use. We searched the literature and reviewed existing case reports of celecoxib-induced liver injury to highlight similarities and offer a discussion of the associated pathology.
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Although drug-induced liver injury is common, physician awareness of specific drug reactions is often limited. Celecoxib-induced drug injury has not been widely reported. We describe the case of a 28 year-old woman who presented to the emergency department with cholestatic liver injury following 13 days of celecoxib use. We searched the literature and reviewed existing case reports of celecoxib-induced liver injury to highlight similarities and offer a discussion of the associated pathology.
Key concepts: Celecoxib, Medicine, Liver injury, Emergency department, Drug, Intensive care medicine, Internal medicine, Pharmacology