ScholarLens Back to search
1985•The Journal of AntibioticsOpen access

Antibacterial activity of cefminox against anaerobes.

Kunitomo Watanabe, Kakuyo SAWA, Midori Bunai, Kazue Ueno

Open full text 6 citations

Abstract

The antibacterial activity of cefminox (CMNX) against anaerobic bacteria was studied in vitro. The results are as follows: 1. CMNX exerted antibacterial activity against a wide range of anaerobes, excluding Clostridium innocuum. The antibacterial activity of CMNX against Bacteroides fragilis was comparable to that of latamoxef and superior to cefoxitin, but CMNX's activity against anaerobic cocci was slightly inferior to cefoxitin's; 2. A comparison of the MICs and MBCs of CMNX indicated that this drug exerts a complete bactericidal effect at a concentration which inhibits the growth of bacteria; 3. CMNX was found to be stable to the beta-lactamases produced by B. fragilis; 4. CMNX exerted an antibacterial activity against C. difficile.

Open-access reader

About this research paper

What this paper is about

The antibacterial activity of cefminox (CMNX) against anaerobic bacteria was studied in vitro. The results are as follows: 1. CMNX exerted antibacterial activity against a wide range of anaerobes, excluding Clostridium innocuum. The antibacterial activity of CMNX against Bacteroides fragilis was comparable to that of latamoxef and superior to cefoxitin, but CMNX's activity against anaerobic cocci was slightly inferior to cefoxitin's; 2. A comparison of the MICs and MBCs of CMNX indicated that this drug exerts a complete bactericidal effect at a concentration which inhibits the growth of bacteria; 3. CMNX was found to be stable to the beta-lactamases produced by B. fragilis; 4. CMNX exerted an antibacterial activity against C. difficile.

Why it matters

OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

The antibacterial activity of cefminox (CMNX) against anaerobic bacteria was studied in vitro. The results are as follows: 1. CMNX exerted antibacterial activity against a wide range of anaerobes, excluding Clostridium innocuum. The antibacterial activity of CMNX against Bacteroides fragilis was comparable to that of latamoxef and superior to cefoxitin, but CMNX's activity against anaerobic cocci was slightly inferior to cefoxitin's; 2. A comparison of the MICs and MBCs of CMNX indicated that this drug exerts a complete bactericidal effect at a concentration which inhibits the growth of bacteria; 3. CMNX was found to be stable to the beta-lactamases produced by B. fragilis; 4. CMNX exerted an antibacterial activity against C. difficile.

Key concepts: Bacteroides fragilis, Cefoxitin, Microbiology, Antibacterial activity, Anaerobic bacteria, Latamoxef, Peptostreptococcus, Bacteria

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Antibacterial activity of cefminox against anaerobes. — Research Paper | ScholarLens