2010•Cutaneous and Ocular ToxicologyRequires access
Use of autologous whole blood during internal limiting membrane peeling and macular hole surgery is protective for indocyanine green toxicity
Lan‐Hsin Chuang, Nan‐Kai Wang, Ling Yeung, Yen‐Po Chen, Yih-Shiou Hwang, Wei‐Chi Wu, Chi‐Chun Lai
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Abstract
OBJECTIVE: To compare indocyanine green (ICG)-assisted internal limiting membrane (ILM) peeling with and without autologous whole blood (WB) protection during macular hole repair surgery. MATERIAL AND METHODS: We retrospectively reviewed 50 eyes with an idiopathic macular hole. Group 1 contained 22 eyes that underwent ILM peeling with WB protection and group 2 contained 28 eyes that underwent ILM peeling without WB. Anatomic and visual results were compared. RESULTS: After surgery, macular hole closure was achieved in 96% of the group 1 eyes and in 93% of the group 2 eyes. The preoperative mean best-corrected visual acuity (BCVA) was logarithm of the minimum angle of resolution (logMAR) 0.95 in group 1 and logMAR 0.89 in group 2 (p = .544). The postoperative mean BCVA was logMAR 0.57 in group 1 and logMAR 0.92 in group 2 (p = .017). CONCLUSION: Macular hole surgery protected with WB facilitates improved visual recovery in ICG-assisted ILM peeling.