2004•The Pediatric Infectious Disease JournalRequires access
AZITHROMYCIN AS AN ALTERNATIVE TO NALIDIXIC ACID IN THE THERAPY OF CHILDHOOD SHIGELLOSIS
Dan Miron, Moshe S. Torem, Rivka Merom, Raul Colodner
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Abstract
In an outbreak of shigellosis in a kibbutz in Northeastern Israel, oral nalidixic acid failed clinically in 35% and microbiologically in 28.4% of 14 children as compared with no clinical and microbiologic failure in 25 children who were treated with oral azithromycin (P < 0.01 and 0.012, respectively). Thus azithromycin could be a suitable alternative to nalidixic acid.