2003BloodRequires access

Hypoxia-inducible factors and marrow stromal function

Peter Curtin

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Abstract

Multicellular organisms have developed complex organ systems for the uptake, transport, and delivery of oxygen. Many processes involved in oxygen homeostasis are mediated by hypoxia-inducible factors (HIFs), which control the transcription of a number of target genes. Initially identified as the key

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What this paper is about

Multicellular organisms have developed complex organ systems for the uptake, transport, and delivery of oxygen. Many processes involved in oxygen homeostasis are mediated by hypoxia-inducible factors (HIFs), which control the transcription of a number of target genes. Initially identified as the key

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Available abstract

Multicellular organisms have developed complex organ systems for the uptake, transport, and delivery of oxygen. Many processes involved in oxygen homeostasis are mediated by hypoxia-inducible factors (HIFs), which control the transcription of a number of target genes. Initially identified as the key

Key concepts: Hypoxia (environmental), Bone marrow, Stromal cell, Medicine, Biology, Pathology, Cancer research, Immunology

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