1991Current Opinion in LipidologyRequires access

Apolipoprotein and lipoprotein synthesis and modifications

Vassilis I. Zannis, Christos Cladaras, Eleni E. Zanni

Open publisher page 3 citations

Abstract

Conventional and molecular biological approaches have defined the sites of apolipoprotein synthesis and have described intra- and extracellular apolipoprotein modifications. Topics selected for discussion in this review include new aspects of apolipoprotein synthesis and modifications, modification of apolipoprotein B byproducts of lipid oxidation, remodeling of lipoproteins by transfer of apolipoproteins and functional significance, in vivo and in vitro assembly of apolipoprotein B-containing lipoproteins, and intracellular versus extracellular assembly of high-density lipoprotein and lipoprotein-type particles.

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What this paper is about

Conventional and molecular biological approaches have defined the sites of apolipoprotein synthesis and have described intra- and extracellular apolipoprotein modifications. Topics selected for discussion in this review include new aspects of apolipoprotein synthesis and modifications, modification of apolipoprotein B byproducts of lipid oxidation, remodeling of lipoproteins by transfer of apolipoproteins and functional significance, in vivo and in vitro assembly of apolipoprotein B-containing lipoproteins, and intracellular versus extracellular assembly of high-density lipoprotein and lipoprotein-type particles.

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Available abstract

Conventional and molecular biological approaches have defined the sites of apolipoprotein synthesis and have described intra- and extracellular apolipoprotein modifications. Topics selected for discussion in this review include new aspects of apolipoprotein synthesis and modifications, modification of apolipoprotein B byproducts of lipid oxidation, remodeling of lipoproteins by transfer of apolipoproteins and functional significance, in vivo and in vitro assembly of apolipoprotein B-containing lipoproteins, and intracellular versus extracellular assembly of high-density lipoprotein and lipoprotein-type particles.

Key concepts: Apolipoprotein B, Apolipoprotein C2, Lipoprotein, Chemistry, Apolipoprotein E, Extracellular, Biochemistry, Intracellular

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