1980•Proceedings of the National Academy of SciencesOpen access
Apolipoprotein B variant derived from rat intestine.
K. Krishnaiah, Lee Walker, Jayme Borensztajn, Gustav Schonfeld, Godfrey S. Getz
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Abstract
A variant of apolipoprotein B has been observed in the lymph lipoproteins [chylomicrons, very low density lipoproteins (VLDL), and low density lipoproteins (LDL)] of rats, in the plasma VLDL of fed rats, and in the plasma VLDL and LDL of rats fed a high-fat, high-cholesterol diet. It is the sole apolipoprotein B in the chylomicrons and VLDL of lymph. It differs from the apolipoprotein B of normal plasma LDL in its immunological properties and in its apparent molecular weight from electrophoresis on 3.5% NaDodSO4/polyacrylamide gel.