2004•Clinica Chimica ActaRequires access

Metabolic activity of dextromethorphan O-demethylation in healthy Japanese volunteers carrying duplicated CYP2D6 genes: duplicated allele of CYP2D6*10 does not increase CYP2D6 metabolic activity

Akihiro Ishiguro, Takahiro Kubota, Hiroshi Ishikawa, Tatsuji Iga

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Key concepts: Dextromethorphan, CYP2D6, Dextrorphan, Pharmacogenetics, Allele, Biology, Genetics, Pharmacology

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Metabolic activity of dextromethorphan O-demethylation in healthy Japanese volunteers carrying duplicated CYP2D6 genes: duplicated allele of CYP2D6*10 does not increase CYP2D6 metabolic activity — Research Paper | ScholarLens