Correlation of serum and urine dextromethorphan/dextrorphanmetabolic ratio in CYP2D6 phenotyping
Jan Juřica, Richard Barteček, Ondřej Zendulka, Alexandra Žourková
Abstract
Jan Juřica, Richard Barteček, Ondřej Zendulka, Alexandra Žourková
Abstract
The results of investigation of correlation of serum and urine dextromethorphan/dextrorphan metabolic ratio in CYP2D6 phenotyping were presented. Based on genetic analysis and values of MR, cutt off values (MRdem/dor) for separating extensive, poor and intermediate metabolizers were also identfied.
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The results of investigation of correlation of serum and urine dextromethorphan/dextrorphan metabolic ratio in CYP2D6 phenotyping were presented. Based on genetic analysis and values of MR, cutt off values (MRdem/dor) for separating extensive, poor and intermediate metabolizers were also identfied.
Key concepts: Dextrorphan, Dextromethorphan, CYP2D6, Urine, Correlation, Medicine, Pharmacology, Chemistry