2010Unpublished venueRequires access

Correlation of serum and urine dextromethorphan/dextrorphanmetabolic ratio in CYP2D6 phenotyping

Jan Juřica, Richard Barteček, Ondřej Zendulka, Alexandra Žourková

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Abstract

The results of investigation of correlation of serum and urine dextromethorphan/dextrorphan metabolic ratio in CYP2D6 phenotyping were presented. Based on genetic analysis and values of MR, cutt off values (MRdem/dor) for separating extensive, poor and intermediate metabolizers were also identfied.

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The results of investigation of correlation of serum and urine dextromethorphan/dextrorphan metabolic ratio in CYP2D6 phenotyping were presented. Based on genetic analysis and values of MR, cutt off values (MRdem/dor) for separating extensive, poor and intermediate metabolizers were also identfied.

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Available abstract

The results of investigation of correlation of serum and urine dextromethorphan/dextrorphan metabolic ratio in CYP2D6 phenotyping were presented. Based on genetic analysis and values of MR, cutt off values (MRdem/dor) for separating extensive, poor and intermediate metabolizers were also identfied.

Key concepts: Dextrorphan, Dextromethorphan, CYP2D6, Urine, Correlation, Medicine, Pharmacology, Chemistry

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