1990•American Journal of HematologyRequires access

Familial macrothrombocytopenia associated with decreased glycosylation of platelet membrane glycoprotein IV

Yuji Yufu, Hiroshi Ideguchi, Takahiro Narishige, Eiichi Suematsu, Ḱazunori Toyoda, Junji Nishimura, Hajime Nawata, Susumu Oda

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Abstract

A case of hereditary thrombocytopenia with large platelets (familial macrothrombocytopenia, FM) is reported. Studies on the platelets from the propositus showed decreased glycosylation of platelet membrane glycoprotein IV, which would distinguish the case from other FM previously described.

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Key concepts: Glycoprotein, Platelet membrane glycoprotein, Glycosylation, Platelet, Membrane glycoproteins, Medicine, Blood Platelet Disorders, Internal medicine