2000Journal of the American College of CardiologyOpen access

Upregulation of the Bcl-2 family of proteins in end stage heart failure

Najma Latif, Mahboob A. Khan, Emma J. Birks, Aldo O’Farrell, Jules A. Westbrook, Michael J. Dunn, Magdi H. Yacoub

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Key concepts: TUNEL assay, DNA laddering, Terminal deoxynucleotidyl transferase, Apoptosis, DNA fragmentation, In Situ Nick-End Labeling, Downregulation and upregulation, Western blot

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