ScholarLens Back to search
1988•International Journal of HyperthermiaRequires access

Sensitivities of bleomycin-resistant variant cells enhanced by 40°C hyperthermiain vitro

Eiichi Kano, M Furukawa-Furuya, K. Nitta, Tomoko Kajimoto-kinoshita, Porntipa Picha, Kiyoshi Sugimoto, Toshio Ohtsubo, Koh Tsuji, Susumu Tsubouchi, Takashi Kondo

Open publisher page 15 citations

Abstract

Cultured mammalian cells of higher (mouse L) and lower (Chinese hamster V-79) sensitivities to bleomycin (BLM) were repeatedly treated with BLM (0.1 mg/ml), through which BLM-resistant variant strains were induced. Sensitivities of these variant strains to BLM were enhanced by simultaneous treatment with 40 degrees C hyperthermia.

About this research paper

What this paper is about

Cultured mammalian cells of higher (mouse L) and lower (Chinese hamster V-79) sensitivities to bleomycin (BLM) were repeatedly treated with BLM (0.1 mg/ml), through which BLM-resistant variant strains were induced. Sensitivities of these variant strains to BLM were enhanced by simultaneous treatment with 40 degrees C hyperthermia.

Why it matters

OpenAlex reports 15 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Cultured mammalian cells of higher (mouse L) and lower (Chinese hamster V-79) sensitivities to bleomycin (BLM) were repeatedly treated with BLM (0.1 mg/ml), through which BLM-resistant variant strains were induced. Sensitivities of these variant strains to BLM were enhanced by simultaneous treatment with 40 degrees C hyperthermia.

Key concepts: Bleomycin, Chinese hamster, In vitro, Hyperthermia, Molecular biology, Hamster, Biology, Chinese hamster ovary cell

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Sensitivities of bleomycin-resistant variant cells enhanced by 40°C hyperthermiain vitro — Research Paper | ScholarLens