1968Acta PaediatricaRequires access

CHAPTER XIII Treatment of pituitary dwarfism with human growth hormone

Paul Roos

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Abstract

Summary Two mg HGH has been given twice a week to nine patients with pituitary dwarfism and to four children in whom pituitary dwarfism was suspected. All nine patients with proved hypopituitarism increased their growth velocity, the mean height increment during the first year of treatment being 10.5 cm. During the following years the growth velocity approached normal growth. None of the patients became resistant to the treatment and regular tests for antibodies were negative. None of four patients with doubtful hypopituitarism responded to the treatment.

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Summary Two mg HGH has been given twice a week to nine patients with pituitary dwarfism and to four children in whom pituitary dwarfism was suspected. All nine patients with proved hypopituitarism increased their growth velocity, the mean height increment during the first year of treatment being 10.5 cm. During the following years the growth velocity approached normal growth. None of the patients became resistant to the treatment and regular tests for antibodies were negative. None of four patients with doubtful hypopituitarism responded to the treatment.

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Available abstract

Summary Two mg HGH has been given twice a week to nine patients with pituitary dwarfism and to four children in whom pituitary dwarfism was suspected. All nine patients with proved hypopituitarism increased their growth velocity, the mean height increment during the first year of treatment being 10.5 cm. During the following years the growth velocity approached normal growth. None of the patients became resistant to the treatment and regular tests for antibodies were negative. None of four patients with doubtful hypopituitarism responded to the treatment.

Key concepts: Dwarfism, Hypopituitarism, Medicine, Growth hormone, Growth velocity, Internal medicine, Endocrinology, Human growth hormone

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