2010•Gynecologic InvestigationRequires access

In vitro Perfusion Studies of the Human Placenta Angioradiographic Study of the Maternal Circulation (With Colour Plate I)

James E. Rourke, Leo V. Gould, Philip A. Rice, R.E.L. Nesbitt

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Abstract

The flow of maternal perfusate through the intervillous space has been monitored by observing the flow of a radiopaque injection. The results of these experiments show that the extracorporeal apparatus devised by us does provide adequate perfusion of the isolated placenta in a manner strikingly similar to that occurring in vivo. Supporting evidence was obtained by dissecting the placenta to locate the distribution of India ink injected with the radiopaque dye.

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What this paper is about

The flow of maternal perfusate through the intervillous space has been monitored by observing the flow of a radiopaque injection. The results of these experiments show that the extracorporeal apparatus devised by us does provide adequate perfusion of the isolated placenta in a manner strikingly similar to that occurring in vivo. Supporting evidence was obtained by dissecting the placenta to locate the distribution of India ink injected with the radiopaque dye.

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Available abstract

The flow of maternal perfusate through the intervillous space has been monitored by observing the flow of a radiopaque injection. The results of these experiments show that the extracorporeal apparatus devised by us does provide adequate perfusion of the isolated placenta in a manner strikingly similar to that occurring in vivo. Supporting evidence was obtained by dissecting the placenta to locate the distribution of India ink injected with the radiopaque dye.

Key concepts: Intervillous space, Placenta, Perfusion, Placental Circulation, Human placenta, In vivo, Extracorporeal circulation, Fetal circulation

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