Imaging with Radioactive Microspheres to Demonstrate Maternal Circulation in the Placenta of Rhesus Monkeys
A. Everette James, Michael Eric Siegel, Elizabeth Mapelsden Ramsey, Maurice Panigel, R Misenhimer, Martin W. Donner
Abstract
A. Everette James, Michael Eric Siegel, Elizabeth Mapelsden Ramsey, Maurice Panigel, R Misenhimer, Martin W. Donner
Abstract
Utilizing contrast and radionuclide angiography, scans, specimens radiographs, and histological examination, the placental circulation was studied to determine whether maternal placental blood flow is uniform and if large arteriovenous shunts are present in the placenta. Five rhesus monkeys of approximately 110 days gestation were studied. The blood flow to the placenta was found to be heterogenous with greater regional blood flow at the points of entry of spiral arteries into the intervillous space. No large arteriovenous shunts were demonstrated in 4 of 5 animals.
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Utilizing contrast and radionuclide angiography, scans, specimens radiographs, and histological examination, the placental circulation was studied to determine whether maternal placental blood flow is uniform and if large arteriovenous shunts are present in the placenta. Five rhesus monkeys of approximately 110 days gestation were studied. The blood flow to the placenta was found to be heterogenous with greater regional blood flow at the points of entry of spiral arteries into the intervillous space. No large arteriovenous shunts were demonstrated in 4 of 5 animals.
Key concepts: Intervillous space, Placenta, Placental Circulation, Blood flow, Medicine, Blood circulation, Angiography, Microsphere