2009•Kidney InternationalOpen access

Biomechanical strain causes maladaptive gene regulation, contributing to Alport glomerular disease

Daniel T. Meehan, Duane Delimont, Linda Cheung, Marisa Zallocchi, Steven C. Sansom, J. David Holzclaw, Velidi H. Rao, Dominic Cosgrove

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Key concepts: Alport syndrome, Glomerular basement membrane, Glomerulonephritis, Proteinuria, Basement membrane, Glomerulosclerosis, Internal medicine, Matrix metalloproteinase

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Biomechanical strain causes maladaptive gene regulation, contributing to Alport glomerular disease — Research Paper | ScholarLens