Synthesis of 7,10- and 7,8-dimethylbenz[c]acridine
CECILE PENE, Jean‐Marc Lhoste, P Markovits, M. Hubert‐Habart
Abstract
CECILE PENE, Jean‐Marc Lhoste, P Markovits, M. Hubert‐Habart
Abstract
7,10-Dimethylbenz[c]acridine, commonly used in experimental cancerology, is shown to be a mixture with 7,8-dimethylbenz[c]acridine. Unambiguous syntheses of these two dimethylbenz[c]acridine are described.
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7,10-Dimethylbenz[c]acridine, commonly used in experimental cancerology, is shown to be a mixture with 7,8-dimethylbenz[c]acridine. Unambiguous syntheses of these two dimethylbenz[c]acridine are described.
Key concepts: Acridine, Acridine derivatives, Chemistry, Stereochemistry, Organic chemistry