Pradeep Kumar, Shweta Mahajan, Kailash C. Gupta
Abstract
A new efficient reusable universal polymer support for oligonucleotide synthesis, based on a non-ammoniacal cleavable linker, is described. Twenty six cycles of oligonucleotide synthesis have been carried out without compromising the quality of the fully deprotected oligonucleotides.
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A new efficient reusable universal polymer support for oligonucleotide synthesis, based on a non-ammoniacal cleavable linker, is described. Twenty six cycles of oligonucleotide synthesis have been carried out without compromising the quality of the fully deprotected oligonucleotides.
Key concepts: Oligonucleotide, Chemistry, Oligonucleotide synthesis, Linker, Polymer, Combinatorial chemistry, Organic chemistry, Biochemistry