e0492 Carotid intimia-media thickness and coronary artery disease

Objective To analyse the relationship of carotid atherosclerotic and coronary artery disease (CAD), by measuring Carotid intimia - media thickness. Methods The plaque index and intimia - media thickness (IMT) were detected by high-resolution ultrasound in patients with coronary artery angiography. The extent of difference of IMT were compared between patients with and without coronary artery disease. Results Compared to the patients with no CAD, the IMT of patients with CAD significantly increased (0.83±0.08 mm vs 0.91±0.11 mm; 0.83±0.08 mm MS1.08±0.15 mm; 0.91±0.11 mm MS1.08±0.15 mm; p<0.05). The incidence of plaque in CAD patients was higher than that of patients with no CAD. The IMT was significantly higher in multi-vessel group than those in uni-vessel group p<0.05). Conclusion In CAD patients, the widened inner diameter and lower blood flow rate of carotid artery result in a maximal shearing force significantly lower than that of the control group.The increasing intima-media thickness is associated greatly with carotid atherosclerosis.The haemodynamics change plays an important role in the development and progression of atherosclerosis in CAD patients. Carotid atherosclerosis has great value in predicting coronary artery disease. The IMT can be the surrogate markers of the extensive of coronary artery lesion.