Effects of delayed percutaneous coronary intervention on left ventricle remodeling in patients with acute myocardial infarction

Objective To assess the effect of delayed percutaneous coronary intervention (PCI) on left ventricle remodeling after acute myocardial infarction (AMI). Methods Ninety six patients with ST-segment elevation acute interior wall myocardial infarction (AAMI) and with the total occluded left anterior descending coronary artery conformed by angiography at 10.2±2.5 (7∼14) days after onset were divided into two groups according to stent implantation: PCI group and control group. To detect the left ventricular function (LVEF), left ventricular end-diastolic volume index (LVEDVI), left ventricular end-systolic volume index (LVESVI) and left ventricular wall motion abnormality (VWMA), two dimensional echocardiogram was performed before operation (9.0±2.5 days after AMI) and at 2 and 6 months after onset of AAMI respectively. Results LVEF, LVEDVI, LVESVI and VWMA score were similar in two groups before operation and 2 months after the onset of AAMI, LVEF and VWMA scores did not changed significantly at 6 months in each group compared with those before operation and at 2 months (p>0.05). But LVEDVI and LVESVI were improved significantly in the successful PCI group than those before operation and in the control group (p<0.01, p<0.05). Conclusions Delayed PCI in AAMI might prevent the late phase but not the early phase of left ventricular remodeling.