Carsten Behrens, Otto Dahl
Abstract
Full experimental procedures for the synthesis of a series of new functional linker reagents (14-16) and solid supports (11-13) are reported. The achiral linker reagents and supports can be used for high yield incorporation of free amino groups, fluorescein or biotin into DNA oligomers.
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Full experimental procedures for the synthesis of a series of new functional linker reagents (14-16) and solid supports (11-13) are reported. The achiral linker reagents and supports can be used for high yield incorporation of free amino groups, fluorescein or biotin into DNA oligomers.
Key concepts: Linker, Reagent, Labelling, Oligonucleotide, Combinatorial chemistry, Yield (engineering), Chemistry, Biotin