2012•Pharmaceutical ResearchOpen access

Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone Effects on iNOS mRNA Expression and Nitric Oxide During LPS-Induced Inflammation in Rats

Siddharth Sukumaran, Eve‐Irene Lepist, Debra C. DuBois, Richard R. Almon, William J. Jusko

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Key concepts: Nitric oxide, Nitric oxide synthase, Chemistry, Inflammation, Pharmacology, Pharmacokinetics, Lipopolysaccharide, Methylprednisolone

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Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone Effects on iNOS mRNA Expression and Nitric Oxide During LPS-Induced Inflammation in Rats — Research Paper | ScholarLens