1979•Annals of NeurologyRequires access
Thrombocytopenia associated with sodium valproate treatment
Andreas N. Neophytides, John G. Nutt, Jules R. Lodish
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Abstract
The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.