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2005•Biochemical and Biophysical Research CommunicationsRequires access

The N588K-HERG K+ channel mutation in the ‘short QT syndrome’: Mechanism of gain-in-function determined at 37 °C

Mark J. McPate, Rona S. Duncan, James T. Milnes, Harry J. Witchel, Jules C. Hancox

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Key concepts: hERG, Short QT syndrome, Chemistry, Long QT syndrome, Sudden death, Patch clamp, Chinese hamster ovary cell, Voltage clamp

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The N588K-HERG K+ channel mutation in the ‘short QT syndrome’: Mechanism of gain-in-function determined at 37 °C — Research Paper | ScholarLens