Advances in Study of LQT2 Syndrome-Related HERG Gene
Lou Jian-shi
Abstract
Lou Jian-shi
Abstract
The protein that HERG gene encodes is very important in cardiac repolarization, and HERG gene mutation will lead to inherited long QT syndrome. Acquired long QT syndrome is also associated with the HERG gene. As molecular genetic research proceeds, the molecular mechanism whereby HERG gene mutation causes long QT syndrome is being gradually revealed.
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The protein that HERG gene encodes is very important in cardiac repolarization, and HERG gene mutation will lead to inherited long QT syndrome. Acquired long QT syndrome is also associated with the HERG gene. As molecular genetic research proceeds, the molecular mechanism whereby HERG gene mutation causes long QT syndrome is being gradually revealed.
Key concepts: hERG, Long QT syndrome, Medicine, Mutation, Repolarization, Gene, QT interval, Gene mutation