1985•Poultry ScienceOpen access

Vaccination Against Marek's Disease and Infectious Bursal Disease III. Growth Rate of Both Turkey Herpesvirus and Infectious Bursal Disease Virus in Coinfected Cell Cultures

Jui-Yuan Chang, C. S. Eidson, S. H. Kleven

Abstract

Titers of the turkey herpesvirus (HVT) and infectious bursal disease virus (IBDV) in coinfected cell cultures, used to produce a live bivalent HVT/IBDV vaccine, were determined daily. Based on the daily titers, cells harvested either 2 or 3 days after inoculating the second virus (IBDV) into HVT infected cell cultures yielded the maximum titers for both viruses. Harvesting coinfected cell cultures on either day provided the most suitable source of the live HVT/IBDV vaccine against Marek's disease and infectious bursal disease.

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Key concepts: Infectious bursal disease, Virology, Virus, Titer, Inoculation, Vaccination, Marek's disease, Biology