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2008•Journal of Immunology and ImmunopathologyRequires access

Host-pathogen interaction in infectious bursal disease (IBD): Target of IBD virus on chicken bursal B cells

Daya P Gangale, Hari Mohan Saxena

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Abstract

Infectious Bursal Disease (IBD) is an acute contagious disease of young chickens with high morbidity and low mortality causing heavy losses to poultry industry worldwide. The disease is caused by IBD virus (IBDV), an Avibirnavirus which infects immature bursal B-cells of young chicken. However, the target molecule of B cells for binding of IBDV is not known. This review attempts to discuss the various possibilities and the current research in this direction.

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What this paper is about

Infectious Bursal Disease (IBD) is an acute contagious disease of young chickens with high morbidity and low mortality causing heavy losses to poultry industry worldwide. The disease is caused by IBD virus (IBDV), an Avibirnavirus which infects immature bursal B-cells of young chicken. However, the target molecule of B cells for binding of IBDV is not known. This review attempts to discuss the various possibilities and the current research in this direction.

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Available abstract

Infectious Bursal Disease (IBD) is an acute contagious disease of young chickens with high morbidity and low mortality causing heavy losses to poultry industry worldwide. The disease is caused by IBD virus (IBDV), an Avibirnavirus which infects immature bursal B-cells of young chicken. However, the target molecule of B cells for binding of IBDV is not known. This review attempts to discuss the various possibilities and the current research in this direction.

Key concepts: Infectious bursal disease, Virus, Virology, Pathogen, Disease, Biology, Medicine, Immunology

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