Olsalazine as an Alternative Therapy in a Patient with Sulfasalazine-Induced Eosinophilic Pneumonia
Joost Scherpenisse, P.D.L.P.M. van der Valk, Jules M.M. van den Bosch, P. A. M. van Hees, J. H. S. M. Nadorp
Abstract
Joost Scherpenisse, P.D.L.P.M. van der Valk, Jules M.M. van den Bosch, P. A. M. van Hees, J. H. S. M. Nadorp
Abstract
A man with Crohn's colitis developed eosinophilic pneumonia after treatment with sulfasalazine. Challenge with sulfapyridine revealed that this component of sulfasalazine was the likely causative agent. Treatment with olsalazine, a 5-aminosalicylic acid compound (disodium-azodisalicylate), was well tolerated without recurrence of pulmonary symptoms.
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A man with Crohn's colitis developed eosinophilic pneumonia after treatment with sulfasalazine. Challenge with sulfapyridine revealed that this component of sulfasalazine was the likely causative agent. Treatment with olsalazine, a 5-aminosalicylic acid compound (disodium-azodisalicylate), was well tolerated without recurrence of pulmonary symptoms.
Key concepts: Sulfasalazine, Sulfapyridine, Medicine, Eosinophilic pneumonia, Eosinophilic, Pneumonia, Gastroenterology, Internal medicine