Muhammad Taha, Nor Hadiani Ismail, Syahrul Imran, Khalid Mohammed Khan
Abstract
4-(5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzohydrazide (5) was synthesized by three steps. The synthesis started with 2-methoxybenzohydrazide to form hydrazone (3) which was then cyclized to oxadiazole (4) and finally, treatment of oxadiazole (4) with hydrazine hydrate afforded the final product (5).
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4-(5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzohydrazide (5) was synthesized by three steps. The synthesis started with 2-methoxybenzohydrazide to form hydrazone (3) which was then cyclized to oxadiazole (4) and finally, treatment of oxadiazole (4) with hydrazine hydrate afforded the final product (5).
Key concepts: Hydrazone, Oxadiazole, Chemistry, Hydrazine (antidepressant), Hydrate, Combinatorial chemistry, Organic chemistry, Medicinal chemistry