2012•Bioorganic & Medicinal Chemistry LettersOpen access

Discovery and evaluation of selective N-type calcium channel blockers: 6-Unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives

Takashi Yamamoto, Seiji Niwa, Munetaka Tokumasu, Tomoyuki Onishi, Seiji Ohno, Masako Hagihara, Hajime Koganei, Shin‐ichi Fujita, Tomoko Takeda, Yuki Saitou, Satoshi Iwayama, Akira Takahara, Seinosuke Iwata, Masataka Shoji

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Key concepts: Chemistry, Dihydropyridine, Calcium channel, N-type calcium channel, Pyridine, Calcium, Calcium channel blocker, Carboxylic acid