Changes in the blood coagulation profile after ovariohysterectomy in female dogs
Przemysław Sobiech, Ryszard Targoński, Artur Stopyra, Katarzyna Żarczyńska
Abstract
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Przemysław Sobiech, Ryszard Targoński, Artur Stopyra, Katarzyna Żarczyńska
Abstract
Open-access reader
This study investigated changes in the coagulation profile of 10 healthy female dogs subjected to ovariohysterectomy. Blood samples were collected three times--before, directly after and 24 h after surgery. Plasma samples were analyzed to determine thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen content, D-dimer content and antithrombin (AT) III activity. The results revealed post-operative haemostatic system disorders related to prolonged APTT, higher fibrinogen and D-dimer concentrations and lower levels of AT III activity.
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This study investigated changes in the coagulation profile of 10 healthy female dogs subjected to ovariohysterectomy. Blood samples were collected three times--before, directly after and 24 h after surgery. Plasma samples were analyzed to determine thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen content, D-dimer content and antithrombin (AT) III activity. The results revealed post-operative haemostatic system disorders related to prolonged APTT, higher fibrinogen and D-dimer concentrations and lower levels of AT III activity.
Key concepts: Partial thromboplastin time, Fibrinogen, Prothrombin time, Thrombin time, Antithrombin, Coagulation, Medicine, Internal medicine