József Aszódi, Jean‐François Chantot, Jeannine Collard, Georges Teutsch
Abstract
Abstract Coupling reaction of the aromatic sulfenyl chlorides (II) with the diazopyruvate (III) followed by cyclization with the mercaptomethylazetidinone (I) yields the isocephamcarboxylates (IV) which are dehydrated and deprotected to give the isocephemcarboxylic acids (VI).
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Abstract Coupling reaction of the aromatic sulfenyl chlorides (II) with the diazopyruvate (III) followed by cyclization with the mercaptomethylazetidinone (I) yields the isocephamcarboxylates (IV) which are dehydrated and deprotected to give the isocephemcarboxylic acids (VI).
Key concepts: Chemistry, Thio-, Aryl, Alkyl, Medicinal chemistry, Organic chemistry, Combinatorial chemistry