2013Journal for ImmunoTherapy of CancerOpen access

Combination immunotherapy with Interleukin-2 and CTLA-4 blockade decreases tumor growth and improves overall survival

Joseph R. Broucek, Tasha M. Hughes, Erica J. Huelsmann, Joseph L Poshepny, Carl E. Ruby, Andrew Zloza, Howard L. Kaufman

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Abstract

Meeting abstracts Combination immunotherapy is quickly gaining attention in the field of cancer treatment. IL-2, a cytokine which activates T cells, and ipilimumab, a monoclonal antibody that blocks CTLA-4, are both approved as monotherapy for metastatic melanoma. To date, combination immunotherapy

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Meeting abstracts Combination immunotherapy is quickly gaining attention in the field of cancer treatment. IL-2, a cytokine which activates T cells, and ipilimumab, a monoclonal antibody that blocks CTLA-4, are both approved as monotherapy for metastatic melanoma. To date, combination immunotherapy

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Available abstract

Meeting abstracts Combination immunotherapy is quickly gaining attention in the field of cancer treatment. IL-2, a cytokine which activates T cells, and ipilimumab, a monoclonal antibody that blocks CTLA-4, are both approved as monotherapy for metastatic melanoma. To date, combination immunotherapy

Key concepts: Ipilimumab, Medicine, Immunotherapy, CTLA-4, Blockade, Monoclonal antibody, Metastatic melanoma, Cancer immunotherapy

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