IPILIMUMAB IN THERAPY OF METASTATIC MELANOMA

Metastatic melanoma remains a refractory disease. Great progress in therapy of metastatic melanoma patients has been made in the recent five years. Targeted immunotherapy – a selective effect on lymphocytes signal molecules - became a principally new trend in the drug therapy of tumors. Ipilimumab is the first drug of this class that demonstrated clinical effectiveness in metastatic melanoma patients. This article deals with a review of the latest data of internal studies and own clinical experience of ipilimumab application in metastatic melanoma patients.