1998•The Kitakanto Medical JournalOpen access

An Immunohistochemichal Study of Peripheral Nerve Sheath Tumors by a Novel Marker (Schwann/2E Antibody) of Schwann Cells and Myelin of the Peripheral Nervous System.

Hanako Arai, Yoichi Nakazato

Abstract

シュワン細胞と末梢性髄鞘に特異的に反応するSchwann/2E抗体を用いて, 神経鞘腫92例, 悪性神経鞘腫6例, 神経線維腫12例, 外傷性神経腫3例を免疫組織化学的に検索した.神経鞘腫の78%にSchwann/2E陽性細胞が出現しており, 37%の症例では全体の1/3以上の細胞がSchwann/2E陽性であった.悪性神経鞘腫と神経線維腫は全例がSchwann/2E陰性であった.外傷性神経腫では大部分の細胞がSchwann/2E陽性となった.以上の結果から, Schwann/2E抗体のシュワン細胞由来腫瘍における特徴的な染色性ならびにそれら腫瘍の検索におけるSchwann/2E抗体の有用性が示された.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Schwann cell, Peripheral nervous system, Myelin, Myelin sheath, Peripheral nerve, Neuroscience, Biology, Pathology