2015•Mutation Research/Genetic Toxicology and Environmental MutagenesisRequires access

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Yoshifumi Uno, Hajime Kojima, Takashi Omori, Raffaella Corvi, Masamistu Honma, Leonard M. Schechtman, Raymond R. Tice, Carol Beevers, Marlies De Boeck, Brian Burlinson, Cheryl A. Hobbs, Sachiko Kitamoto, Andrew R. Kraynak, James P. McNamee, Yuzuki Nakagawa, Kamala Pant, Ulla Plappert‐Helbig, Catherine C. Priestley, Hironao Takasawa, Kunio Wada, Uta Wirnitzer, Norihide Asano, Patricia A. Escobar, David Lovell, Takeshi Morita, Madoka Nakajima, Yasuo Ohno, Makoto Hayashi

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Key concepts: Comet assay, Carcinogen, Genotoxicity, In vivo, Toxicology, Chemistry, Computational biology, DNA damage