X-ray phase contrast microscopy at 300 nm resolution with laboratory sources
Daniele Pelliccia, Andrea Sorrentino, Inna Bukreeva, Alessia Cedola, F. Scarinci, Mihaela Ilie, Annamaria Gerardino, Michela Fratini, S. Lagomarsino
Abstract
Daniele Pelliccia, Andrea Sorrentino, Inna Bukreeva, Alessia Cedola, F. Scarinci, Mihaela Ilie, Annamaria Gerardino, Michela Fratini, S. Lagomarsino
Abstract
We report the performance of an X-ray phase contrast microscope for laboratory sources with 300 nm spatial resolution. The microscope is based on a commercial X-ray microfocus source equipped with a planar X-ray waveguide able to produce a sub-micrometer x-ray beam in one dimension. Phase contrast images of representative samples are reported. The achieved contrast and resolution is discussed for different configurations. The proposed approach could represent a simple, inexpensive, solution for sub-micrometer resolution imaging with small laboratory setups.
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We report the performance of an X-ray phase contrast microscope for laboratory sources with 300 nm spatial resolution. The microscope is based on a commercial X-ray microfocus source equipped with a planar X-ray waveguide able to produce a sub-micrometer x-ray beam in one dimension. Phase contrast images of representative samples are reported. The achieved contrast and resolution is discussed for different configurations. The proposed approach could represent a simple, inexpensive, solution for sub-micrometer resolution imaging with small laboratory setups.
Key concepts: Optics, Phase-contrast imaging, Resolution (logic), Microscope, Micrometer, Microscopy, Phase contrast microscopy, Materials science