Lipid Peroxidation in Human Erythrocytes in Tocopherol Deficiency
G. R. Tudhope, J. G. Hopkins
Abstract
G. R. Tudhope, J. G. Hopkins
Abstract
Lipid peroxidation following exposure to H2O2 vapour was abnormally great in the erythrocytes from certain patients with low plasma tocopherol concentrations. Following treatment of such patients with tocopherol, erythrocyte lipid peroxidation was markedly reduced. The in vitro addition of tocopherol reduced lipid peroxidation in erythrocytes from both normal subjects and tocopherol-deficient patients.
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Lipid peroxidation following exposure to H2O2 vapour was abnormally great in the erythrocytes from certain patients with low plasma tocopherol concentrations. Following treatment of such patients with tocopherol, erythrocyte lipid peroxidation was markedly reduced. The in vitro addition of tocopherol reduced lipid peroxidation in erythrocytes from both normal subjects and tocopherol-deficient patients.
Key concepts: Lipid peroxidation, Tocopherol, Vitamin E, Chemistry, Biochemistry, alpha-Tocopherol, In vitro, Antioxidant