Synthesis and Reactions of Some Novel Mercaptopyrimidine Derivatives for Biological Evaluation
Hayam H. Sayed, Ahmed H. Moustafa, N. M. Yousif, Mohamed G. Assy, M. A. Abd El-Halim
Abstract
Hayam H. Sayed, Ahmed H. Moustafa, N. M. Yousif, Mohamed G. Assy, M. A. Abd El-Halim
Abstract
4-Mercapto-5-acetylpyrimidine derivative was used as a precursor for preparation of some novel thieno[2,3-d]pyrimidine, pyrazolo[2,3-d]pyrimidine, isothiazolo [5,4-d] pyrimidine, pyrrolo[4,5-d]pyrimidine, and pyrimidio[4,5-d]pyrimidine derivatives. Furthermore, some of the prepared products were revealed promising antimicrobial activities.
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4-Mercapto-5-acetylpyrimidine derivative was used as a precursor for preparation of some novel thieno[2,3-d]pyrimidine, pyrazolo[2,3-d]pyrimidine, isothiazolo [5,4-d] pyrimidine, pyrrolo[4,5-d]pyrimidine, and pyrimidio[4,5-d]pyrimidine derivatives. Furthermore, some of the prepared products were revealed promising antimicrobial activities.
Key concepts: Pyrimidine, Chemistry, Derivative (finance), Combinatorial chemistry, Antimicrobial, Stereochemistry, Organic chemistry, Financial economics