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Severe Hypoglycemia in Elderly Patients Receiving Therapeutic Doses of Tolbutamide

Pierce Gardner, Charles J. Goodner, J. Thomas Dowling

Open publisher page 12 citations

Abstract

Severe hypoglycemia occurred without warning in three elderly diabetic subjects while they were receiving moderate therapeutic doses of tolbutamide. The clinical picture of the condition mimicked cerebral vascular accident, thereby leading to diagnostic confusion. Severe hypoglycemia during tolbutamide therapy is apparently quite rare. Because of the large number of elderly people taking tolbutamide, in evaluating apparent cerebral vascular accidents in this group, a high index of suspicion of drug-induced hypoglycemia is recommended.

About this research paper

What this paper is about

Severe hypoglycemia occurred without warning in three elderly diabetic subjects while they were receiving moderate therapeutic doses of tolbutamide. The clinical picture of the condition mimicked cerebral vascular accident, thereby leading to diagnostic confusion. Severe hypoglycemia during tolbutamide therapy is apparently quite rare. Because of the large number of elderly people taking tolbutamide, in evaluating apparent cerebral vascular accidents in this group, a high index of suspicion of drug-induced hypoglycemia is recommended.

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OpenAlex reports 12 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Severe hypoglycemia occurred without warning in three elderly diabetic subjects while they were receiving moderate therapeutic doses of tolbutamide. The clinical picture of the condition mimicked cerebral vascular accident, thereby leading to diagnostic confusion. Severe hypoglycemia during tolbutamide therapy is apparently quite rare. Because of the large number of elderly people taking tolbutamide, in evaluating apparent cerebral vascular accidents in this group, a high index of suspicion of drug-induced hypoglycemia is recommended.

Key concepts: Tolbutamide, Medicine, Hypoglycemia, Confusion, Anesthesia, Pediatrics, Diabetes mellitus, Intensive care medicine

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