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Hyperthermia after discontinuance of levodopa and bromocriptine therapy

Ladislao Figà-Talamanca, Carla Gualandi, Luciana Di Meo, Giancarlo Di Battista, Giuseppe Neri, Francesca Lo Russo

Open publisher page 80 citations

Abstract

Hyperthermia, with no signs of any underlying infection, may occur in the course of neuroleptic malignant syndrome, fatal catatonia, heat stroke, or malignant hyperthermia. We describe hyperthermia as a complication after discontinuance of antiparkinsonian treatment with levodopa/carbidopa and bromocriptine. Impaired nigrostriatal, hypothalamic, and mesolimbic dopaminergic functions could be involved in pathogenesis.

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What this paper is about

Hyperthermia, with no signs of any underlying infection, may occur in the course of neuroleptic malignant syndrome, fatal catatonia, heat stroke, or malignant hyperthermia. We describe hyperthermia as a complication after discontinuance of antiparkinsonian treatment with levodopa/carbidopa and bromocriptine. Impaired nigrostriatal, hypothalamic, and mesolimbic dopaminergic functions could be involved in pathogenesis.

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OpenAlex reports 80 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Hyperthermia, with no signs of any underlying infection, may occur in the course of neuroleptic malignant syndrome, fatal catatonia, heat stroke, or malignant hyperthermia. We describe hyperthermia as a complication after discontinuance of antiparkinsonian treatment with levodopa/carbidopa and bromocriptine. Impaired nigrostriatal, hypothalamic, and mesolimbic dopaminergic functions could be involved in pathogenesis.

Key concepts: Bromocriptine, Carbidopa, Levodopa, Hyperthermia, Neuroleptic malignant syndrome, Medicine, Dopamine receptor, Dopaminergic

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