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1991•The British Journal of PsychiatryRequires access

The Treatment of Neuroleptic Malignant Syndrome are Dantrolene and Bromocriptine Useful Adjuncts to Supportive Care?

Patricia I. Rosebush, Thomas E. Stewart, Michael F. Mazurek

Open publisher page 126 citations

Abstract

In a prospective study of 20 patients with NMS, those who received dantrolene (2 patients) or bromocriptine (2 patients) or both (4 patients) tended to have a more prolonged course of illness and a greater incidence of sequelae than those treated with supportive care alone. These results do not indicate a useful role for dantrolene or bromocriptine in the treatment of NMS.

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What this paper is about

In a prospective study of 20 patients with NMS, those who received dantrolene (2 patients) or bromocriptine (2 patients) or both (4 patients) tended to have a more prolonged course of illness and a greater incidence of sequelae than those treated with supportive care alone. These results do not indicate a useful role for dantrolene or bromocriptine in the treatment of NMS.

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OpenAlex reports 126 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

In a prospective study of 20 patients with NMS, those who received dantrolene (2 patients) or bromocriptine (2 patients) or both (4 patients) tended to have a more prolonged course of illness and a greater incidence of sequelae than those treated with supportive care alone. These results do not indicate a useful role for dantrolene or bromocriptine in the treatment of NMS.

Key concepts: Dantrolene, Bromocriptine, Medicine, Neuroleptic malignant syndrome, Incidence (geometry), Anesthesia, Internal medicine, Prolactin

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The Treatment of Neuroleptic Malignant Syndrome are Dantrolene and Bromocriptine Useful Adjuncts to Supportive Care? — Research Paper | ScholarLens