1990Phosphorus, sulfur, and silicon and the related elementsRequires access

Paosphorothioate Analogues of Inositol Phosphates

Allan M. Cooke, Leroy James, Stefan R. Nahorski, Barry V. L. Potter

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Abstract

Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.

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What this paper is about

Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.

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Available abstract

Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.

Key concepts: Inositol, Inositol phosphate, Second messenger system, Intracellular, Phosphate, Chemistry, Inositol trisphosphate receptor, Biochemistry

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