1994•Bulletin of the Chemical Society of JapanRequires access

Synthesis of 2-Substituted myo-Inositol 1,3,4,5-Tetrakis(phosphate) and 1,3,4,5,6-Pentakis(phosphate) Analogs

Shoichiro Ozaki, Yasuji Koga, Lei Ling, Yutaka Watanabe, Yuichi Kimura, Masato Hirata

Abstract

Abstract Some biologically interesting inositol poly(phosphate) derivatives, 2-O-(p-aminobenzoyl)-myo-inositol 1,3,4,5-tetrakis(phosphate), 2-O-(4-aminocyclohexylcarbonyl)-myo-inositol 1,3,4,5-tetrakis(phosphate), myo-inositol 1,3,4,5,6-pentakis(phosphate), and its 2-substituted analogs, were synthesized. Inositol tetrakis(phosphate) and pentakis(phosphate) affinity columns were also prepared. The inositol 1,3,4,5-tetrakis(phosphate) affinity column was found to be effetive in isolating the binding proteins from bovine cardiac membranes.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 33 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Chemistry, Phosphate, Inositol, Inositol phosphate, Cyclitol, Membrane, Phosphate buffered saline, Stereochemistry