1978•The Kurume Medical JournalOpen access
VARIOUS AUTOANTIBODIES IN HASHIMOT0'S THYROIDITIS
Nobumitsu Okita, Kenichi Kodama, Yoichi Ito, Jiro Nakayama, KENICHI NAKASHIMA, Kenichiro Iimori, TERUO TOYOMASU, MARIKO KUHARA, KAZUO ANEGAWA, Masaro Kaji, T Yoshizumi
Open full text 3 citations
Abstract
The relationship between humoral autoantibodies and endocrinological and histological findings of thyroid gland were studied in 45 subjects with Hashimoto's thyroiditis. The positive reaction of autoantibodies were these, thyroglobulin antibody 53.1 % ; anti-microsome antibody 85 .5 % antinuclear factor 40 % parietal cell antibody 28.9 % ; smooth muscle antibody 10.5 % and anti-insulin antibody 2.5 %. The negative reaction were these, anti-thyroxine antibody, abnormal binding of thyroxine to gammaglobulin and anti-DNA antibody. The correlation between these autoantibodies and endocrinological and histological findings of thyroid gland were not significant, while the parietal cell antibody was thought to be correlated with hypothyroid state of Hashimoto's thyroiditis.
Open-access reader