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Unstable Genetic Elements Affecting Streptomycin Resistance in the Streptomycin-producing Organisms Streptomyces griseus NCIB 8506 and Streptomyces bikiniensis ISP 5235

R. Kirby, Eastman M. Lewis

Open publisher page 21 citations

Abstract

There have been many cases in Streptomyces where a phenotype has proved to be unstable. This has usually been taken to suggest plasmid involvement. In the case of streptomycin resistance in two strains, this instability is reversible. Moreover, its cyclic nature suggests that insertion by a transposable element is affecting expression of a gene or genes.

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What this paper is about

There have been many cases in Streptomyces where a phenotype has proved to be unstable. This has usually been taken to suggest plasmid involvement. In the case of streptomycin resistance in two strains, this instability is reversible. Moreover, its cyclic nature suggests that insertion by a transposable element is affecting expression of a gene or genes.

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OpenAlex reports 21 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

There have been many cases in Streptomyces where a phenotype has proved to be unstable. This has usually been taken to suggest plasmid involvement. In the case of streptomycin resistance in two strains, this instability is reversible. Moreover, its cyclic nature suggests that insertion by a transposable element is affecting expression of a gene or genes.

Key concepts: Streptomyces griseus, Streptomycin, Streptomyces, Transposable element, Plasmid, Biology, Microbiology, Streptomycetaceae

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Unstable Genetic Elements Affecting Streptomycin Resistance in the Streptomycin-producing Organisms Streptomyces griseus NCIB 8506 and Streptomyces bikiniensis ISP 5235 — Research Paper | ScholarLens